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Wellbutrin XL (Bupropion)
Product of Canada - Manufactured by Taro Pharmaceuticals Inc.
Bupropion is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder (SAD) which is sometimes called winter depression.
Bupropion may also be used for purposes not listed in this medication guide.
Tablet, sustained-release (Wellbutrin SR)
Tablet, extended-release (Wellbutrin XL)
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use exactly as directed by your healthcare provider.
You may take bupropion with or without food.
The usual starting dose for adults is 200 mg a day, given in two doses of 100 mg (bupropion SR). After which your doctor may increase your dose which will be given in divided doses; with at least a six-hour interval between doses.
The extended release (Wellbutrin XL) is usually started at 150mg given once a day in the morning within a 24-hour time frame.
Try to take your bupropion (Wellbutrin XL) at the same time each day and avoid it being too close to bedtime.
Do not crush, chew, or break your bupropion tablet. Swallow it whole.
You should not change your dose or stop using bupropion suddenly, without consulting your doctor. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using bupropion.
Bupropion can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.
If you miss a dose, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Store at room temperature; away from moisture, heat, and light.
You should not take bupropion if you are allergic to it, or if you have:
- a seizure disorder;
- an eating disorder such as anorexia or bulimia; or
- if you have suddenly stopped using alcohol, seizure medication, or a sedative such as Xanax, Valium, Fiorinal, Klonopin, and others).
Bupropion is not approved for use by anyone younger than 18 years old.
Drinking alcohol and using illegal drugs with bupropion may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can also cause seizures in a regular drinker who suddenly stops drinking at the start of treatment with bupropion.
Bupropion may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Bupropion may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.
To make sure bupropion is safe for you, tell your doctor if you have:
- a history of head injury, seizures, or brain or spinal cord tumor;
- narrow-angle glaucoma;
- been diagnosed with an eating disorder such as anorexia or bulimia;
- heart disease, high blood pressure, history of heart attack;
- kidney or liver disease (especially cirrhosis);
- bipolar disorder or other mental illness; or
- abruptly stopped drinking or are still drinking alcohol or
- had an allergic reaction to bupropion previously.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Bupropion can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, depression, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
- a seizure (convulsions);
- unusual changes in mood or behavior;
- shortness of breath;
- swollen glands;
- increased frequency of urination;
- a manic episode–racing thoughts, increased energy, reckless behavior, feeling extremely happy or irritable, talking more than usual, severe problems with sleep;
- blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- fast heartbeats; or
- severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- dry mouth, stuffy nose;
- nausea, constipation;
- sleep problems (insomnia);
- feeling anxious;
- dizziness; or
- joint pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Tell your doctor about all your other medicines, especially:
- drugs that reduce the threshold for seizures such as prochlorperazine (Compazine), chlorpromazine (Thorazine), etc.;
- benzodiazepines such as diazepam (Valium), alprazolam (Xanax);
- Carbamazepine (Tegretol)
- Ritonavir (Norvir)
- MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Do not take bupropion to treat more than one condition at a time.
This list is not complete. Many drugs may affect this medication, including prescription and over-the-counter medicines, vitamins, and herbal products.
Seek emergency medical attention
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Customer Questions & Answers
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Our average regular delivery time for generic Wellbutrin XL (Bupropion) is 10 days from our Canadian online pharmacy. Delivery times for Wellbutrin XL (Bupropion) do vary depending on the location of the dispensary. The reason deliveries take time is primarily due to customs procedures that need to be completed prior to allowing our packages to enter the United States. Expedited and tracked delivery services are available from our Canadian online dispensary. Please speak to one of our online pharmacy service representatives if you have any questions about delivery times for your order.
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According to the National Institute of Mental Health, approximately 5.7 million adult Americans are affected by bipolar disorder. With all forms of bipolar disorder, the patient will typically experience episodes of depression. Bipolar disorder involves fluctuation between hypomania or mania (“high”) and clinical depression (“low”).
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