Could not find your medication ? Call us!

Similar Products

Discreet Packaging

Two package of Canada Post
Your order for Premarin Vaginal Cream will be shipped in discreet packaging so whether the item is shipped to your home or work no one will know the contents of the shipment until opened.

Customer Reviews

Premarin Vaginal Cream (conjugated estrogens cream)

Premarin Vaginal Cream

Select product strength:



Premarin Vaginal Cream
Estrogens, Conjugated

Prescription Required

0.625 mg/g 30 g $99.52

Product of Canada - Manufactured by Pfizer Inc

0.625 mg/g 60 g $183.04

Product of Canada - Manufactured by Pfizer Inc

0.625 mg/g 90 g $265.56

Product of Canada - Manufactured by Pfizer Inc

Premarin Vaginal Cream
Estrogens, Conjugated

Prescription Required

0.625 mg/g 28 g $83.27

Product of Canada - Manufactured by Pfizer Inc

0.625 mg/g 56 g $142.53

Product of Canada - Manufactured by Pfizer Inc

0.625 mg/g 84 g $183.80

Product of Canada - Manufactured by Pfizer Inc

Frequently Purchased Together
Product Information ​
Premarin-Vaginal-Cream Menopause Medication-30g/tube

*Product images are for reference only

Brand Names

  • ​Premarin Vaginal Cream


Estrogens are female sex hormones produced by the ovaries. Estrogens are necessary for many processes in the body. Conjugated estrogens are a mixture of estrogen hormones.

Premarin Vaginal Cream is used locally in the vaginal area to treat the vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse.

Vaginal cream with applicator

  •  0.625 mg/g

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use Premarin vaginal cream exactly as directed.

Premarin Vaginal Cream is usually prescribed for daily use only for the first two weeks of therapy. Afterwards, a maintenance dose of two to three times per week is sufficient for most patients.

Follow your doctor’s instructions.

To apply this medication, use only the vaginal applicator provided. After each use, take the applicator apart and clean it with mild soap and warm water. Do not use hot or boiling water.

Store at room temperature away from moisture and heat.

You should not use Premarin Vaginal Cream if you are allergic to any of its ingredients. You should not use this medicine if you have:

  • undiagnosed vaginal bleeding;
  • liver disease;
  • a bleeding disorder;
  • had a heart attack, a stroke, a blood clot; or
  • cancer of the breast, uterus/cervix, or vagina.

If you will have major surgery, or are pregnant you should not use this medication

Use effective birth control if you are not past menopause. Tell your doctor if you think you may be pregnant.

Report any unusual vaginal bleeding right away.
This medicine is not approved for use by anyone younger than 18 years old.

Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using estrogen.

Avoid using other vaginal products without your doctor’s advice.

Tell your doctor if you have ever had : 

  • heart disease; 
  • liver problems, or jaundice caused by pregnancy or taking hormones; 
  • kidney disease;
  • gallbladder disease;
  • epilepsy or other seizure disorder;
  • migraines;
  • lupus;
  • endometriosis or uterine fibroid tumors;
  • hereditary angioedema;
  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous
  • system);

Premarin Vaginal Cream can weaken the latex of a condom, diaphragm, or cervical cap. Talk to your doctor about the best birth control methods to use.

Please tell your doctor or pharmacist if you are using or have recently used any other medicines, including medicines obtained without a prescription, herbal medicines or other natural products.

However, Premarin Vaginal Cream is used for a local treatment in the vagina and is not likely to affect other medicines.

Premarin Vaginal Cream may affect other vaginally applied treatments.

Get emergency medical help if you have ​signs of an allergic reaction:​ hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • heart attack symptoms–chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • signs of a stroke–sudden numbness or weakness(especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
  • signs of a blood clot–sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
  • swelling or tenderness in your stomach;
  • jaundice (yellowing of the skin or eyes);
  • memory problems, confusion, unusual behavior;
  • unusual vaginal bleeding, pelvic pain;
  • a lump in your breast; or

Common side effects may include:

  • headache;
  • flushing (warmth, redness, or tingly feeling);
  • breast tenderness; or
  • vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding.

If you have used more Conjugated Estrogens Vaginal than you should, talk to a doctor or pharmacist immediately.

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, seek emergency medical attention.

If you have any questions about buying discount ​Premarin Vaginal Cream​ or any other prescription products online, you can contact us.


Notice: The above information is an educational aid only. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Customer Questions & Answers

If you have questions about this product, fill the form bellow and one of our patient representatives will be happy to answer your questions

    Delivery Timetable

    Our average regular delivery time for Premarin Vaginal Cream is 10 days from our Canadian online pharmacy. Delivery times for Premarin Vaginal Cream do vary depending on the location of the dispensary. The reason deliveries take time is primarily due to customs procedures that need to be completed prior to allowing our packages to enter the United States. Expedited and tracked delivery services are available from our Canadian online dispensary. Please speak to one of our online pharmacy service representatives if you have any questions about delivery times for your order.

    Related Articles

    4 women happy on the mountain.

    Premarin – Conjugated Estrogen for Relief of the Symptoms of Menopause

    Estrogen is a hormone produced by the ovaries. When a woman nears or reaches menopause the ovaries produce less estrogen. For many women, menopause brings with it several uncomfortable symptoms such as weight gain, sleep problems, chills, mood changes, hot flashes, irregular periods, vaginal dryness and night sweats.

    Menopause Medication Category Image- A smiling woman standing in big yard.

    How Vagifem® Helps Relieve Menopausal Symptoms

    Vagifem® is a type of hormone therapy (HT) called local estrogen therapy. Unlike some other horomone therapies which deliver estrogen to the entire body, this therapy delivers estrogen directly to the uterus and vagina., is your #1 Canadian Mail Order Pharmacy service offering access to thousands of safe, affordable, reliable, brand-name and generic prescription medications from our licensed, tier one, CIPA certified full-service pharmacy partners; order online today or call us at 1-800-399-3784.

    About our partner pharmacies: CanadaOnlineHealth only works with CIPA approved dispensaries from countries such as Canada, Britain, Australia, and New Zealand. All of our pharmacy partners are licensed in the jurisdiction where they are located. What this means is CanadaOnlineHealth is working with licensed health care professionals in licensed pharmacies around the world. We have direct relationships with pharmacies in Canada, the UK, Australia, and New Zealand. Your first line of contact is with our pharmacy partner in Canada. Our licensed pharmacist partners in Canada are happy to address all of your pharmacy related health care concerns. By carefully reviewing your prescriptions our pharmacy partners ensure both the accuracy and safety of your order, considering both the appropriateness of the order and the possibility of any drug interactions you need to be made aware of. Please be sure to share all of your current medications with our staff when opening an account with us so our partner pharmacies may consider all possible drug related issues.